Anal rectal disfunction

Study record managers: refer to the Data Element Definitions if submitting registration or results information. The majority of patients with multiple sclerosis MS suffer from some form of anorectal dysfunction, and these difficulties with bowel function are often ranked as negatively impactful on quality of life as impaired mobility. Despite the significant clinical burden of these symptoms, there remains a paucity of published literature supporting specific therapeutic options to manage anorectal dysfunction in this clinical population. Most bowel regimens rely on either oral laxatives i. PEG or anti-diarrheal agents i. In their study, the investigators propose to establish the efficacy of a bowel regimen that combines both oral agents as needed; standard care with scheduled, every other day dosing of a placebo or stimulant laxative rectal suppository -- bisacodyl 10 mg.
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Advances in the evaluation of anorectal function

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Pelvic Floor Dysfunction Expanded Version | ASCRS

The primary functions of the rectum and pelvic floor muscles are to prevent incontinence loss of control and to allow defecation to occur. This requires intact sensation as well as normal anatomy and coordination to work as it should. In certain situations, an inability to relax the pelvic floor muscles or certain anatomic changes can lead to difficulty getting stool out, which is called pelvic floor dysfunction also known as pelvic floor dyssynergia, obstructive defecation, or anismus. On the other hand, damage to the pelvic floor can lead to undesired leakage of stool, called fecal incontinence. This most commonly happens from damage that occurs from childbirth in women, or from radiation for prostate cancer in men, although there are many other causes. For more information, click here.
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Anorectal Dysfunction

Pelvic floor dysfunction includes a group of disorders causing abnormalities of bowel storage and bowel emptying, as well as pelvic pain. This information is intended to help patients gain a better understanding of the disorders making up pelvic floor dysfunction, as well as the evaluation and treatment of pelvic floor dysfunction. It is intended to help patients who suspect that they may have pelvic floor dysfunction better understand the reason for their symptoms, and help them realize that with proper evaluation and treatment it is possible to get relief from symptoms that can be quite disabling. Patients should know that a thorough, step-wise approach to evaluate their symptoms may offer prompt diagnosis and treatment for what often is a long-standing, frustrating problem.
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